Posted by:
Dave the Atheist
(
)
Date: November 26, 2021 09:39AM
"The variant harbours a large number of mutations found in other variants, including Delta, and it seems to be spreading quickly across South Africa. A World Health Organization (WHO) expert group will meet on 26 November, and will likely label the strain — currently known as B.1.1.529 — as a variant of concern or variant of interest. The variant would likely be named Nu if it is flagged by the WHO group.
A top priority is to track the variant more closely as it spreads: it was first identified in Botswana this month and has turned up in travellers to Hong Kong from South Africa. Scientists are also trying to understand the variant’s properties, such as whether it can evade immune responses triggered by vaccines and whether it causes more or less severe disease than other variants do.
Researchers spotted B.1.1.529 in genome-sequencing data from Botswana. The variant stood out because it contains more than 30 changes to the spike protein — the SARS-CoV-2 protein that recognizes host cells and is the main target of the body’s immune responses. Many of the changes have been found in variants such as Delta and Alpha and are linked to heightened infectivity and the ability to evade infection-blocking antibodies.
Researchers in South Africa will also study whether B.1.1.529 causes disease that is more severe or milder than other variants produce, Lessells said. “The really key question comes around disease severity.”
https://www.nature.com/articles/d41586-021-03552-w