Posted by:
Elder Berry
(
)
Date: November 04, 2020 04:39PM
"Alzheimer’s Disease appears to occur only in humans but not even in humans’ close relatives, such as chimpanzees (Finch and Stanford 2004)."
Would you feel the advantage of using Chimpanzees to test this hypothesis worth the unethical approach?
"One hypothesis for the development of Alzheimer’s Disease is that oligomers of beta amyloid are toxic to human neurons (Geula et al. 1998). A reasonable experimental approach to evaluating this idea would be to determine whether beta amyloid was less toxic to neurons from a range of nonhuman primates, particularly humans’ close relatives, like chimpanzees, that do not get the disease. However, for ethical reasons, isolated chimpanzee neurons are difficult to obtain."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140272/