Posted by:
[|]
(
)
Date: September 30, 2020 07:27PM
https://www.nature.com/articles/s41586-020-2818-3Abstract
A recent genetic association study1 identified a gene cluster on chromosome 3 as a risk locus for respiratory failure upon SARS-CoV-2 infection. A new study2 comprising 3,199 hospitalized COVID-19 patients and controls finds that this is the major genetic risk factor for severe SARS-CoV-2 infection and hospitalization (COVID-19 Host Genetics Initiative). Here, we show that the risk is conferred by a genomic segment of ~50 kb that is inherited from Neanderthals and is carried by ~50% of people in South Asia and ~16% of people in Europe today
For thosr who want to wade deeply into the weeds, here is the whole paper
https://www.nature.com/articles/s41586-020-2818-3.epdf?sharing_token=EpB52HO-pg4HSKnaQeBYjdRgN0jAjWel9jnR3ZoTv0MLcfiSFm2PKr9jeM7FZtJjsbUNWozZQ8UWa9r5M17moupqOHSLNDfyseXp2PLVE6f8Kt8BdJOLKGGdKlL6R-niTvFIpNdLtU6yZ6h9ttjJX6joCfb_6R4UC0jxMCP8DeE%3D