Cayenne pepper regulates the flow of blood from the head to the feet so that the pressure is equalized; it influences the heart immediately, then gradually extends its effects to the arteries, capillaries, and nerves (the frequency of the pulse is not increased, but is given more vigor).
The fictional character Sherlock Holmes was an avid user of cocaine. In real life, cocaine is the best memory-enhancing drug known. But the side effects negate its usefulness. Long term usage contributes to paranoia, delusion, anxiety and, ironically, loss of memory. There is a "honey comb" hollowing out of neural functions in the hemispheres.
Alfred Kinsey, the sexual behaviour researcher, had a collection of 5 Million Wasps, and would masturbate by pushing a toothbrush, bristle end first, into his urethra. [source - "Bonk! The study of sexual physiology", by Mary Roach]
That reminds me: the capitol of Holland is Amsterdam but the government seat is in The Hague. To prevent intercity envy, The Hague was denied a city charter and is officially a village. The Dutch are all about compromise!
A spoonful of nutmeg, eaten straight, will have the same effect on your mind as smoking marijuana, but will make you violently ill thirty minutes later.
Not like shroom, not even close. But yes, they will make you hallucinate. Just don't eat the ones sold at local nurseries. They poison them on purpose.